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Farhad Niknejad

Golestan University of Medical Sciences, Iran

Title: Antimicrobial activity of TiO2 alone and combined with ultraviolet-C light on common gram positive Bacillus and fungi contaminated in the herbal drug industry

Biography

Biography: Farhad Niknejad

Abstract

Introduction: Effective and widespread photo catalytic techniques are being developed for applications including disinfection, water cleaning, air pollution, pharmaceutical and food industry, biological and environmental problems. Since the structured and chemical composition of the spores of bacteria is rough and provisionally non fertile, the resistance of the gram positive bacteria species like Bacillus spores that commonly live in soil and water, to a vast range of chemicals and UV light are 5 to 50 times more than their vegetative cells. Due to the antibacterial activity of UV light and photo-catalysts such as (TiO2) titanium dioxide, TiO2/UV, they are being examined as a viable inactivation to a wide range of harmful microorganisms and providing as a treatment of pathogenic bacteria.

Materials & Methods: In this study the photocatalytic deactivation of two fungiʼs spores (Aspergillus parasiticus and Candida albicans) and spore of bacteria (Bcillus subtilis and Bacillus cereus) were investigated by using Tio2 NPs (0.1-2 g/L) and UV light in a reactor.

Results: The activity of UV and TiO2 increased with exposure time to 2 hours. TiO2 alone did not show significant antibacterial and antifungal activity.

Conclusion: These results showed that the quantity of sterilization could be affected by the type of catalyst, exposure time, UV wavelength and average nanoparticle size and the photocatalytic disinfection against spore species. They were mainly effective in UVC and the rate of inactivation improved by the presence of TiO2 NPs and increasing the exposure time. These particles could be used as a significant fungicide and bactericide in agricultural applications and food industry.