Sao Paulo State University, Brazil
Title: Behavior of alveolar and peri-implantar bone affected by osteoporosis and its treatment
Biography: Leonardo Faverani and Roberta Okamoto
Osteoporosis is one of the systemic changes that is of worldwide public health concern, characterized by a decreased bone mass and a deterioration of bone microstructure. Several drugs has been used to osteoporosis treatment with the main goal to increase the bone mineral density and decrease the bone fractures. In dentistry, one of the determining factors for the proper dental implants osseointegration is the quality of bone tissue which is impaired in this situation. Therefore, we aim in this presentation to show the behavior of alveolar bone and peri-implantar bone affected by osteoporosis and its treatment through in vivo studies. In the begining, we will show the alveolar bone in homeostasis situation and then we will discuss some of our studies about alveolar and peri-implantar bone healing in osteoporatic rats treated with different drugs such as estrogen replacement, biphosphonates, selective estrogen receptor modulators and other current medications indicated to treatment of female and male osteoporosis. Our results will be presented through histology, histometric, immunohistochemistry, microtomographic, fluorochromes and molecular analysis, leading to clinical responses.